刘国良

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刘国良

讲师

 

研究方向

1. 新型发光纳米簇的合成和功能;

2. 纳米生物技术与传感

联系方式

办公室

化工楼317

E-mail

glliu@ycit.edu.cn

联系电话

18305101165

教育经历

2010.092013.06

2006.092009.06

2000.092004.06

暨南大学

汕头大学

河南师范大学

生物化学与分子生物学

生物化学与分子生物学

生命科学

博士

硕士

学士

工作经历

2013.07至今

盐城工学院

讲师

荣誉与奖励

1.      2017年江苏省高等学校微课教学比赛二等奖

2.      盐城工学院第二届微课教学比赛一等奖

研究项目

1.      主持江苏省自然科学基金项目靶向激活型荧光纳米探针的癌细胞成像和热疗化疗研究(BK20150424

2.      主持广东省有序结构材料的制备与应用重点实验室开放课题基于DNA模板铜簇的合成及其荧光性质的研究(KLPAOSM201507

3.      主持江苏省海洋滩涂生物化学与生物技术重点建设实验室开放课题基于双嵌段寡核苷酸的光散射纳米生物传感器研究(K2016-18

4.      主持盐城工学院人才引进项目(KJC2014016)。

代表性论文

1.      Guoliang Liu, Jingjing Li, Da-Qian Feng, Jun-Jie Zhu, Wei Wang*, Silver nanoclusters beacon as stimuli-responsive versatile platform for multiplex DNAs detection and aptamer−substrate complexes sensing, Anal. Chem., 2017, 89(1), 1002-1008.

2.      Guoliang Liu, Da-Qian Feng*, Dongliang Hua, Tianhao Liu, Gang Qi, Wei Wang*, Fluorescence enhancement of terminal amine assembled on gold nanoclusters and its application to ratiometric lysine detection. Langmuir, 2017, 33(51), 14643-14648.

3.      Da-Qian Feng, Guoliang Liu*, Wei Wang*, A novel biosensor for copper (II) ions based on turn-on resonance light scattering of ssDNA templated silver nanoclusters. J. Mater. Chem. B, 2015, 3, 2083-2088.

4.      Weihua Zhu, Chenglei Xuan, Guoliang Liu*, Zhuo Chen, Wei Wang*, A label-free fluorescent biosensor for determination of bovine serum albumin and calf thymus DNA based on gold nanorods coated with acridine orange-loaded mesoporous silica, Sensor. Actuat. B, 2015, 220, 302-308.

5.      Guoliang Liu, Da-Qian Feng, Wenjie Zheng, Tianfeng Chen, Dan Li*, An anti-galvanic replacement reaction of DNA template silver nanoclusters monitored by the light-scattering technique. Chem. Commun., 2013, 49, 7941-7943.

6.      Guoliang Liu, Da-Qian Feng*, Zhiyi Li, Yang Feng, Target-activatable gold nanoparticle-based aptasensing for protein biomarkers using stimuli-responsive aggregation. Talanta, 2019, 192, 112-117.

7.      Guoliang Liu, Zhuo Chen, Xiaoying Jiang, Da-Qian Feng, Junyu Zhao, Dahe Fan, Wei Wang*, In-situ hydrothermal synthesis of molecularly imprinted polymers coated carbon dots for fluorescent detection of bisphenol A, Sensor. Actuat. B, 2016, 228, 302-307.

8.      Da-Qian Feng, Guoliang Liu*, Gangpo Ma, Zhe Nan, Wei Wang, Phosphodiesters quaternary ammonium nanoparticles as label-free light scattering probe for turn-off detection of tyrosine. Spectrochim. Acta A, 2019, 208, 1-6.

9.      Da-Qian Feng, Wenjie Zhu, Guoliang Liu*, Wei Wang*, Dual-modal light scattering and fluorometric detection of lead ion by stimuli-responsive aggregation of BSA-stabilized copper nanoclusters. RSC Adv., 2016, 6(99), 96729-96734.

10.  Guoliang Liu, Chenglei Xuan, Da-Qian Feng*, Dongliang Hua, Tianhao Liu, Gang Qi, and Wei Wang*, Dual-modal fluorescence and light-scattering sensor based on water-soluble carbon dots for silver ions detection. Anal.Methods, 2017, 9(38), 5611-5617.

11.  Da-Qian Feng‡, Guoliang Liu, Wenjie Zheng, Tianfeng Chen, Dan Li*, A new light-scattering sensor for screening G-quadruplex stabilizers based on DNA folding-mediated assembly of gold nanoparticles. J. Mater. Chem. B, 2013, 1, 3057-3063.

12.  Da-Qian Feng, Guoliang Liu, Wenjie Zheng, Jie Liu, Tianfeng Chen, Dan Li*, A highly selective and sensitive on-off sensor for silver ions and cysteine by light scattering technique of DNA-functionalized gold nanoparticles. Chem. Commun., 2011, 47, 8557-8559.

13.  Guoliang Liu, Da-Qian Feng‡, Tianfeng Chen, Dan Li*, Wenjie Zheng*, DNA-templated formation of silver nanoclusters as a novel light-scattering sensor for label-free copper ions detection, J. Mater. Chem., 2012, 22, 20885-20888.

14.  Guoliang Liu, Da-Qian Feng, Xiaoyu Mu, Wenjie Zheng, Tianfeng Chen, Li Qi, and Dan Li*, DNA-functionalized silver nanoclusters as a chemopalette: tunable fluorescence for turn-on detection of cysteine. J. Mater. Chem. B, 2013, 1, 2128-2131.

15.  Da-Qian Feng, Meng Chen, Guoliang Liu, Wenjie Zhu, Wensheng Sun, Rong Zhu, Wei Wang*, A novel resonance light scattering sensing for glucose based on the conversion of gold nanoclusters into gold nanoparticles,  Sensor. Actuat. B, 2015, 219, 133-138.

16.  Xiaoying Jiang, Da-Qian Feng*, Guoliang Liu, Dahe Fan, Wei Wang*, A fluorescent switch sensor for detection of anticancer drug and ctDNA based on the glutathione stabilized gold nanoclusters. Sensor. Actuat. B, 2016, 228, 302-307.

17.  刘国良,冯大千,顾益霜,刘天豪,王伟,发光铜纳米粒子的制备及其在生化传感、环境监测中的应用综述,盐城工学院学报2017, 30(4), 1-8.

专利

1.      ZL201310544623.0 一种基于发光金纳米簇检测米托蒽醌的方法

2.      ZL201510113041.6 种用于检测牛血清白蛋白的纳米金棒及其制备方法和应用

讲授课程

《纳米材料与技术导论》、《环境与可持续发展》、《生化环境分析》、《环境保护概论》、《能源与环境》、《生命科学趣谈》



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